NECi Superior Enzymes, previously `The Nitrate Elimination Company, Inc.`, is a woman-owned small business located in Michigan`s Upper Peninsula. NECi`s specialty is designing and producing recombinant proteins for inclusion in quantification test kits. Our focus is applying biotechnology methodology to improve analytical chemistry for citizen monitoring, quality control, and beyond. We develop and manufacture enzymes for green analytical chemistry. Our enzymes are reagent grade, meaning that they are manufactured according to strict standards and protocols, ensuring lot-to-lot consistency and ultimate QA/QC.

Company details

334 Hecla Street , Lake Linden , Michigan 49945 USA

Locations Served

Our Distributors

Business Type:
Manufacturer
Industry Type:
Monitoring and Testing - Water Monitoring and Testing
Market Focus:
Globally (various continents)
Year Founded:
1993
Employees:
11-100
Turnover:
less than $1,000,000 US

This company also provides solutions for other industrial applications.
Please, visit the following links for more info:

Why perform analytical testing if it's not going to be accurate or reliable? Enzyme based analytical chemistry offers superior accuracy and reliability while curbing environmental impact, because enzymes are the natural catalysts that exist within nearly every living system to perform specific duties. This makes them excellent candidates as analytical chemistry tools. Here at NECi Superior Enzymes, we develop and produce recombinant, reagent grade enzymes which are formatted for laboratory scientists, automated instruments, citizen monitors, educators, and others. We are committed to advancing analytical chemistry technologies to keep up with a modern world.

Enzyme-based analytical chemistry offers many benefits:

  • Selectivity – Enzymes are able to find “targets” in complex mixtures, reducing sample prep time
  • Sensitivity – Enzymes offer low detection limits in complex mixtures
  • Specificity – Enzymes react ONLY with the target to be analyzed
  • Safety – Enzymes are proteins, meaning non-toxic reagents, no high heat or pressure, heavy metals, or solvents involved

Currently, NECi offers Nitrate Reductase in many formats for accurate, reliable, and environmentally responsible nitrate testing.  Our Nitrate Reductase is available as bulk reagent, reagent packs (enzyme + co-factor), laboratory test kits, reagent packs for automated laboratory equipment, and easy to use test kits for field testing of any water as well as soil, plant, and dry forage extracts.  

Our enzymatic nitrate testing method using nitrate reductase is an approved EPA ATP for nitrate in waste water.  Laboratories adhering to EPA protocols may seek limited use approval for this method until final approval has been reached.  Nitrate analysis by Nitrate Reductase is an approved ASTM Method: D7781.

We are also developing enzymes for testing glycerol, galactose, phosphate, and alcohol, as well as a handheld smartphone-linked photometer for field testing nitrate and phosphate of soil in the field.  We are currently seeking Beta testers for these products.

Our Commitments

'TIY' Mentality
We believe in providing tools for analytical chemistry that anyone can use. We strive for a 'Test it Yourself' mentality within our community, encouraging citizen science, increasing knowledge of the invisible world around us.

Accurate Data
Why waste time testing if the results might be inaccurate? We believe in actionable data - reliable answers that can be used to make important decisions across many applications.

Open-Source Tech
Freely flowing knowledge benefits collaboration, which benefits everyone. Open source technology makes science more accessible to all.

We are an environmental biotechnology company that creates 'reagent grade' enzymes crafted for analytical chemistry. We are dedicated to the application of biotechnology to the solution of environmental problems.  Our nitrate determination products are reliable, cost-effective, and safe for you and the environment.
 
Our company develops and produces recombinant and native enzyme reagents for analytical chemistry. Enzymes are protein catalysts that speed up the myriad reactions that make life possible. Our reagent grade products and test kits are designed from the bottom up for safe use, storage, export, and disposal.
 
Enzyme-based analytical chemistry has real benefits:

  • Selectivity – Enzymes are able to find “targets” in complex mixtures, reducing sample prep time
  • Sensitivity – Enzymes offer low detection limits in complex mixtures
  • Specificity – Enzymes react ONLY with the target to be analyzed
  • Safety – Enzyme-based analysis involves only non-toxic reagents
  • No high heat or pressure, heavy metals, or solvents involved

We Currently Offer Nitrate Reductase for Nitrate Analysis in Various Forms:

  • Simplified test kits for users with no lab training
  • Reagent packs for micro-plate readers and discrete analyzers for high throughput labs
  • Reagents and reagent packs for laboratories with spectrophotometers and other neccesary lab equipment 

During the late 1980's and early 1990s, Dr. Wilbur H. Campbell, conducted research that led to the creation of our company.  Dr. Campbell, Professor of Biochemistry and Molecular Biology at Michigan Technological University, devised a method for producing and extracting the enzyme, nitrate reductase (NaR), from corn leaves.  In 1993, Dr. Campbell and his wife, Ellen Campbell, founded The Nitrate Elimination Company, Inc. (NECi) to bring this enzyme to the market of nitrate detection, monitoring, and remediation. Through further research, Nitrate Reductase was successfully expressed in yeast, and then extracted and purified for the improved recombinant form that we currently offer in our products.

The Nitrate Elimination Company, Inc. is located in Lake Linden, nestled in heart of the Keweenaw peninsula in the UP of Michigan.  Surrounded by the great Lake Superior, the Keweenaw provides an excellent home for NECi.  Here, we create recombinant Nitrate Reductase for the responsible testing of nitrate in a variety of aqueous samples.  This includes drinking water, agricultural water, waste water, soil extracts, plant extracts, food extracts, and more.  We provide kits and reagent packs for laboratories as well as simple, ready to use test kits for novice users. 

We're not just good for nitrate testing, though.  We are constantly researching new applications for enzyme based analytical chemistry.  Some of the current projects underway are enzymes for determining levels of phosphate, alcohol, glycerol, galactose, total nitrogen, and total phosphorus, as well as a handheld photometer to use with our enzymes as part of a multi-parameter, easy to use testing kit.

Why Enzymes?  They present a multitude of benefits in contrast to outdated nitrate detection methods:

  • Selectivity – Enzymes are able to find “targets” in complex mixtures, reducing sample prep time
  • Sensitivity – Enzymes offer low detection limits in complex mixtures
  • Specificity – Enzymes react ONLY with the target to be analyzed
  • Safety – Enzyme-based analysis involves only non-toxic reagents
  • No high heat or pressure, heavy metals, or solvents involved

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