Nonivamide Material Safety Data Sheet

NONIVAMIDE?Material?Safety?Data?Sheet??Date?Prepared:?August?29,?2009? ? ? ?Date?Revised:?October?27,?2010?1.? Identification?of?the?Substance?and?the?Company?Substance:? Nonivamide?(Synthetic?Capsaicin)?CAS#:? 2444-46-4?Synonym:? Pelargonic?acid?vanillylamide?Chemical?Name:? n-(hydroxy-4?methoxy-3?benzyl)?methyl-8?nonen-6?amide?(trans-)?Chemical?Formula:? C17H27NO3?Supplier:? Aversion?Technologies,?Inc?12220?Maycheck?Lane?Bowie,?Maryland?20715?USA?Telephone:? +1-202-657-6300?Emergency:? +1-202-365-9001?Web?Address:? www.aversiontech.com?2.? Composition:?Substance:? Nonivamide?(Synthetic?Capsaicin)?Content?%:? 95%?3.? Hazard?Identification?Potential?Acute?Health?Effects:? Very?hazardous?in?case?of?skin?contact?(irritant),?of?eye??contact?(irritant),?of?ingestion.?Hazardous?in?case?of?skin?contact?(permeator),?of?inhalation.?Severe?over-?exposure?can?result?in?death.?Inflammation?of?the?eye?is?characterized?by?redness,?watering,?and?itching.?Skin?inflammation?is?characterized?by?itching,?scaling,?reddening,?or,?occasionally,?blistering.?Potential?Chronic?Health?Effects:? CARCINOGENIC?EFFECTS:?Not?available.?MUTAGENIC?EFFECTS:?Mutagenic?for?bacteria.?TERATOGENIC?EFFECTS:?Not?available.?DEVELOPMENTAL?TOXICITY:?Not?available.?The?substance?is?toxic?to?lungs,?mucous?membranes.?Repeated?or?prolonged?exposure?to?the?substance?can?produce?target?organs?damage.?Repeated?exposure?to?a??highly?toxic?material?may?produce?general?deterioration?of?health?by?an?accumulation?in?one?or?many?human?organs.?4.? First?Aid?Measures?Eye?Contact:? Check?for?and?remove?any?contact?lenses.?Immediately??flush?eyes?with?running?water?for?at?least?15?minutes,?keeping?eyelids?open.?Cold?water?may?be?used.?Do?not?use?an?eye?ointment.?Seek?medical?attention.?Skin?Contact:? After?contact?with?skin,?wash?immediately?with?plenty?of?water.?Gently?and?thoroughly?wash?the?contaminated?skin?with?running?water?and?non-abrasive?soap.?Be?particularly?careful?to?clean?folds,?crevices,?creases?and?groin.?Cover?the?irritated?skin?with?an?emollient.?If?irritation?persists,?seek?medical?attention.?Wash?contaminated?clothing?before?reusing.?Serious?Skin?Contact:? Wash?with?a?disinfectant?soap?and?cover?the?contaminated?skin?with?an?anti-bacterial?cream.?Seek?immediate?medical?attention.?Inhalation:? Allow?the?victim?to?rest?in?a?well-ventilated?area.?Seek?immediate?medical?attention.?Serious?Inhalation:? Evacuate?the?victim?to?a?safe?area?as?soon?as?possible.?Loosen?tight?clothing?such?as?a?collar,?tie,?belt?or?waistband.?If?breathing?is?difficult,?administer?oxygen.?If?the?victim?is?not?breathing,?perform?mouth-to-mouth?resuscitation.?Seek?medical?attention.?Ingestion:? Do?not?induce?vomiting.?Examine?the?lips?and?mouth?to?ascertain?whether?the?tissues?are?damaged,?a?possible?indication?that?the?toxic?material?was?ingested;?the?absence?of?such?signs,?however,?is?not?conclusive.?Loosen?tight?clothing?such?as?a?collar,?tie,?belt?or?waistband.?If?the?victim?is?not?breathing,?perform?mouth-to-mouth?resuscitation.?Seek?immediate?medical?attention.?Serious?Ingestion:? Not?available.????Material Safety Data Sheet Nonivamide Page 2 of 3 5.?? Fire?Fighting?Measures?Flammability?of?the?Product:? May?be?combustible?at?high?temperature.?Auto-Ignition?Temperature:? Not?available.?Flash?Point:? 113°C?Flammable?Limits:? Not?available.?Products?of?Combustion:? These?products?are?carbon?oxides?(CO,?CO2),?nitrogen?oxides?(NO,?NO2...).?Fire?Hazards?in?Presence?of?Various?Substances:??Not?available.?Explosion?Hazards?in?Presence?of?Various?Substances:??Risks?of?explosion?of?the?product?in?presence?of?mechanical?impact:?Not?available.?Risks?of?explosion?of?the?product?in?presence?of?static?discharge:?Not?available.?Fire?Fighting?Media?and?Instructions:? SMALL?FIRE:?Use?DRY?chemical?powder.??LARGE?FIRE:?Use?water?spray,?fog?or?foam.?Do?not?use?water?jet. 6.? Accidential?Release?Measures?Small?Spill:? Use?appropriate?tools?to?put?the?spilled?solid?in?a?convenient?waste?disposal?container.?Large?Spill:? Use?a?shovel?to?put?the?material?into?a?convenient?waste?disposal?container.?7.? Handling?and?Storage?Precautions:? Keep?locked?up.?Keep?away?from?heat.?Keep?away?from?sources?of?ignition.?Empty?containers?pose?a?fire?risk,?evaporate?the?residue?under?a?fume?hood.?Ground?all?equipment?containing?material.?Do?not?ingest.?Do?not?breathe?dust.?In?case?of?insufficient?ventilation,?wear?suitable?respiratory?equipment?If?ingested,?seek?medical?advice?immediately?and?show?the?container?or?the?label.?Avoid?contact?with?skin?and?eyes?Storage:? Keep?container?dry.?Keep?in?a?cool?place.?Ground?all?equipment?containing?material.?Keep?container?tightly?closed.?Keep?in?a?cool,?well-ventilated?place.?Highly?toxic?or?infectious?materials?should?be?stored?in?a?separate?locked?safety?storage?cabinet?or?room.?8.? Exposure?Controls?Engineering?Controls:? Use?process?enclosures,?local?exhaust?ventilation,?or?other?engineering?controls?to?keep?airborne?levels?below?recommended?exposure?limits.?If?user?operations?generate?dust,?fume?or?mist,?use?ventilation?to?keep?exposure?to?airborne?contaminants?below?the?exposure?limit.?Personal?Protection:? Splash?goggles,?lab?coat,?dust?respirator,?gloves.?Be?sure?to?use?an?approved/certified?respirator?or?equivalent.?Personal?Protection?in?Case?of?a?Large?Spill:?Splash?goggles,?full?suit,?dust?respirator,?boots,?and?gloves.?A?self-contained?breathing?apparatus?should?be?used?to?avoid?inhalation?of?the?product.?Suggested?protective?clothing?might?not?be?sufficient;?consult?a?specialist?BEFORE?handling?this?product.?Exposure?Limits:? Not?available.?9.? Physical?and?chemical?properties?Physical?state?and?appearance:? Solid?Powder?Odor:? Slight?Taste:? Burning?sensation?Molecular?Weight:? 293.41?g/mole?Color:? White?or?off-white?powder?pH?(1%?solution/water):? Not?applicable?Boiling?Point:? 492.7°C?@?760mm?Hg?Melting?Point:? 54-61°C??Critical?Temperature:? Not?available?Specific?Gravity:? 0.94600?@?20°C?Vapor?Pressure:? Not?applicable?Vapor?Density:? Not?available?Volatility:? Not?available?Odor?Threshold:? Not?available?Water/Oil?Dist.?Coeff.:? Not?available?Ionicity?(in?Water):? Not?available?Dispersion?Properties:? See?solubility?in?water,?methanol,?diethyl?ether?Solubility:? Easily?soluble?in?methanol,?diethyl?ether.?Very?slightly?soluble?in?cold?water?10.?? Stability?and?reactivity?Stability:? The?product?is?stable?Instability?Temperature:? Not?available?Conditions?of?Instability:? Not?available?Incompatibility?with?various?substances:? Not?available?Corrosivity:? Non-corrosive?in?presence?of?glass?Special?Remarks?on?Reactivity:? Not?available?Special?Remarks?on?Corrosivity:? Not?available?Polymerization:? No?? ?? ?Material Safety Data Sheet Nonivamide Page 3 of 3 11.?? Toxicology?information?Routes?of?Entry:? Inhalation,?ingestion,?dermal?contact,?eye?contact?Toxicity?to?Animals:? Acute?oral?toxicity?(LD50):?190?mg/kg?(Mouse)?Acute?dermal?toxicity?(LD50):?512?mg/kg?(Mouse)?Chronic?Effects?on?Humans:? The?substance?is?toxic?to?lungs,?mucous?membranes.?Other?Toxic?Effects?on?Humans:? Very?hazardous?in?case?of?skin?contact?(irritant),?of?ingestion.?Hazardous?in?case?of?skin?contact?(permeator),?of?inhalation.?Special?Remarks?on?Toxicity?to?Animals:? Not?available?Special?Remarks?on?Chronic?Effects?on?Humans:?Not?available?Special?Remarks?on?other?Toxic?Effects?on?Humans:?Not?available?12.?? Ecological?Information?Ecotoxicity:? Not?available?BOD5?and?COD:? Not?available?Products?of?Biodegradation:? Possibly?hazardous?short-term?degradation?products?are?not?likely.?However,?long-term?degradation?products?may?arise.?Toxicity?of?the?Products?of?Biodegradation:?The?products?of?degradation?are?more?toxic.?Special?Remarks?on?the?Products?of?Biodegradation:?Not?available.?13.? Disposal?Considerations?Disposal?Methods:? Dispose?of?in?accordance?with?local?authority?requirements.?14.? Transport?information?DOT?Classification:? CLASS?6.1:?Poisonous?material?Identification:? Toxic?solid,?organic,?n.o.s.?(Nonivamide):?UN2811?PG:?III?TSCA:? TSCA?8(b)?inventory:?Nonivamide?(Synthetic?Capsaicin)?Special?Provisions?for?Transport:? Not?available?15.?? Regulatory?Information?Federal?and?State?Regulations:? TSCA?8(b)?inventory:?Nonivamide?(Synthetic?Capsaicin)?Other?Regulations:? ?? OSHA:?? Hazardous?by?definition?of?Hazard?Communication?Standard?(29?CFR1910.1200).?Other?Classifications:? ?? WHMIS?(Canada):?? CLASS?D-1B:?Material?causing?immediate?and?serious?toxic?effects?(TOXIC).?CLASS?D-2B:?Material?causing?other?toxic?effects?(TOXIC).?? DSCL?(EEC):?? R38-?Irritating?to?skin?R41-?Risk?of?serious?damage?to?eyes?? HMIS?(U.S.A.):?? Health?Hazard:?3?Fire?Hazard:?1?Reactivity:?0?Personal?Protection:?E?? National?Fire?Protection?Association?(U.S.A.):??Health:?3?Flammability:?1?Reactivity:?0?Specific?hazard:?? Protective?Equipment:?? Gloves,?lab?coat,?dust?respirator,?splash?goggles.?Be?sure?to?use?an?approved/certified?respirator?or?equivalent.?Wear?appropriate?respirator?when?ventilation?is?inadequate.?16.? Other?Information?DISCLAIMER:?Every?effort?has?been?made?to?ensure?that?this?information?is?accurate?and?up?to?date.?Users?are?reminded?that?they?should?ensure?that?they?have?retained?or?internally?circulated?the?most?up?to?date?copy?as?provided?to?the?persons?or?work?locations?that?require?them.?No?warranty?is?implied?or?given?as?to?suitability?for?use?for?any?activity?that?is?not?covered?by?either?the?technical?data?sheet?or?restrictions?of?use?as?above.????