Trans-Capsaicin Material Safety Data Sheet

TRANS-­-CAPSAICIN  Material  Safety  Data  Sheet    Date  Prepared:  April  5,  20012        Date  Revised:    1.   Identification  of  the  Substance  and  the  Company  Substance:     Trans-­-Capsaicin    CAS#:     404-­-86-­-4  TSCA:     TSCA  8(b)  inventory:  Capsaicin  Synonym:     Pelargonic  acid  vanillylamide  Chemical  Name:     n-­-[(4-­-Hydroxy-­-3-­-methoxybenzyl)-­-8-­-methyl-­-6-­-noneamide  Chemical  Formula:     C18  H27  N  O3    Supplier:     Aversion  Technologies,  Inc.           12220  Maycheck  Lane       Bowie,  Maryland  20715  USA   24-­-Hour  Emergency:  Telephone:   +1-­-202-­-657-­-6300     +1-­-202-­-365-­-9001    Web  Address:   www.aversiontech.com  2.   Composition:  Substance:     Trans-­-Capsaicin  Content  %:   94%  3.   Hazard  Identification  Potential  Acute  Health  Effects:   Very  hazardous  in  case  of  skin  contact  (irritant),  of  eye    contact  (irritant),  of  ingestion.  Hazardous  in  case  of  skin  contact  (permeator),  of  inhalation.  Severe  over-­-  exposure  can  result  in  death.  Inflammation  of  the  eye  is  characterized  by  redness,  watering,  and  itching.  Skin  inflammation  is  characterized  by  itching,  scaling,  reddening,  or,  occasionally,  blistering.  Potential  Chronic  Health  Effects:   CARCINOGENIC  EFFECTS:  Not  available.  MUTAGENIC  EFFECTS:  Mutagenic  for  bacteria.  TERATOGENIC  EFFECTS:  Not  available.  DEVELOPMENTAL  TOXICITY:  Not  available.    The  substance  is  toxic  to  lungs,  mucous  membranes.  Repeated  or  prolonged  exposure  to  the  substance  can  produce  target  organs  damage.  Repeated  exposure  to  a    highly  toxic  material  may  produce  general  deterioration  of  health  by  an  accumulation  in  one  or  many  human  organs.  4.   First  Aid  Measures  Eye  Contact:   Check  for  and  remove  any  contact  lenses.  Immediately    flush  eyes  with  running  water  for  at  least  15  minutes,  keeping  eyelids  open.  Cold  water  may  be  used.  Do  not  use  an  eye  ointment.  Seek  medical  attention.  Skin  Contact:   After  contact  with  skin,  wash  immediately  with  plenty  of  water.  Gently  and  thoroughly  wash  the  contaminated  skin  with  running  water  and  non-­-abrasive  soap.  Be  particularly  careful  to  clean  folds,  crevices,  creases  and  groin.  Cover  the  irritated  skin  with  an  emollient.  If  irritation  persists,  seek  medical  attention.  Wash  contaminated  clothing  before  reusing.  Serious  Skin  Contact:   Wash  with  a  disinfectant  soap  and  cover  the  contaminated  skin  with  an  anti-­-bacterial  cream.  Seek  immediate  medical  attention.  Inhalation:   Allow  the  victim  to  rest  in  a  well-­-ventilated  area.  Seek  immediate  medical  attention.  Serious  Inhalation:   Evacuate  the  victim  to  a  safe  area  as  soon  as  possible.  Loosen  tight  clothing  such  as  a  collar,  tie,  belt  or  waistband.  If  breathing  is  difficult,  administer  oxygen.  If  the  victim  is  not  breathing,  perform  mouth-­-to-­-mouth  resuscitation.  Seek  medical  attention.  Ingestion:   Do  not  induce  vomiting.  Examine  the  lips  and  mouth  to  ascertain  whether  the  tissues  are  damaged,  a  possible  indication  that  the  toxic  material  was  ingested;  the  absence  of  such  signs,  however,  is  not  conclusive.  Loosen  tight  clothing  such  as  a  collar,  tie,  belt  or  waistband.  If  the  victim  is  not  breathing,  perform  mouth-­-to-­-mouth  resuscitation.  Seek  immediate  medical  attention.  Serious  Ingestion:   Not  available.  Material Safety Data Sheet Capsaicin Page 2 of 3 5.     Fire  Fighting  Measures  Flammability  of  the  Product:   May  be  combustible  at  high  temperature.  Auto-­-Ignition  Temperature:   Not  available.  Flash  Points:   Not  available.  Flammable  Limits:   Not  available.  Products  of  Combustion:   These  products  are  carbon  oxides  (CO,  CO2),  nitrogen  oxides  (NO,  NO2...).  Fire  Hazards  in  Presence  of  Various  Substances:    Not  available.  Explosion  Hazards  in  Presence  of  Various  Substances:    Risks  of  explosion  of  the  product  in  presence  of  mechanical  impact:  Not  available.  Risks  of  explosion  of  the  product  in  presence  of  static  discharge:  Not  available.  Fire  Fighting  Media  and  Instructions:   SMALL  FIRE:  Use  DRY  chemical  powder.    LARGE  FIRE:  Use  water  spray,  fog  or  foam.  Do  not  use  water  jet. 6.   Accidential  Release  Measures  Small  Spill:   Use  appropriate  tools  to  put  the  spilled  solid  in  a  convenient  waste  disposal  container.  Large  Spill:   Use  a  shovel  to  put  the  material  into  a  convenient  waste  disposal  container.  7.   Handling  and  Storage  Precautions:   Keep  locked  up.  Keep  away  from  heat.  Keep  away  from  sources  of  ignition.  Empty  containers  pose  a  fire  risk,  evaporate  the  residue  under  a  fume  hood.  Ground  all  equipment  containing  material.  Do  not  ingest.  Do  not  breathe  dust.  In  case  of  insufficient  ventilation,  wear  suitable  respiratory  equipment  If  ingested,  seek  medical  advice  immediately  and  show  the  container  or  the  label.  Avoid  contact  with  skin  and  eyes  Storage:   Keep  container  dry.  Keep  in  a  cool  place.  Ground  all  equipment  containing  material.  Keep  container  tightly  closed.  Keep  in  a  cool,  well-­-ventilated  place.  Highly  toxic  or  infectious  materials  should  be  stored  in  a  separate  locked  safety  storage  cabinet  or  room.  8.   Exposure  Controls  Engineering  Controls:   Use  process  enclosures,  local  exhaust  ventilation,  or  other  engineering  controls  to  keep  airborne  levels  below  recommended  exposure  limits.  If  user  operations  generate  dust,  fume  or  mist,  use  ventilation  to  keep  exposure  to  airborne  contaminants  below  the  exposure  limit.  Personal  Protection:   Splash  goggles,  lab  coat,  dust  respirator,  gloves.  Be  sure  to  use  an  approved/certified  respirator  or  equivalent.  Personal  Protection  in  Case  of  a  Large  Spill:  Splash  goggles,  full  suit,  dust  respirator,  boots,  and  gloves.  A  self-­-contained  breathing  apparatus  should  be  used  to  avoid  inhalation  of  the  product.  Suggested  protective  clothing  might  not  be  sufficient;  consult  a  specialist  BEFORE  handling  this  product.  Exposure  Limits:   Not  available.  9.   Physical  and  chemical  properties  Physical  state  and  appearance:   White  Powder  Odor:   Distinctive  odor  Taste:   Burning  sensation  Molecular  Weight:   305.41  g/mole  Color:   White  to  off-­-white  powder  pH  (1%  solution/water):   Not  applicable  Boiling  Point:   TBD  Melting  Point:   TBD  Flash  Point  (Closed  Cup):   113°C  Specific  Gravity:   Not  available  Vapor  Pressure:   Not  applicable  Vapor  Density:   Not  available  Volatility:   Not  available  Dispersion  Properties:   Insoluble  in  water  Solubility:   Easily  soluble  in  methanol,  diethyl  ether.  Insoluble  in  cold  water  10.     Stability  and  reactivity  Stability:   The  product  is  stable  Instability  Temperature:   Not  available  Conditions  of  Instability:   Excess  heat,  dust  generation,  incompatible  materials  Incompatibility  with  various  substances:   Reactive  with  oxidizing  agents  Corrosivity:   Non-­-corrosive  in  presence  of  glass  Special  Remarks  on  Reactivity:   Not  available  Special  Remarks  on  Corrosivity:   Not  available  Polymerization:   No  11.     Toxicology  information  Routes  of  Entry:   Inhalation,  ingestion.  Toxicity  to  Animals:   Acute  oral  toxicity  (LD50):  148.1  and  161.2  mg/kg  (female  and  male  rat,  respectively)  Acute  dermal  toxicity  (LD50):  512  mg/kg  (Mouse)  Material Safety Data Sheet Capsaicin Page 3 of 3 Chronic  Effects  on  Humans:   The  substance  is  toxic  to  lungs,  mucous  membranes.  Other  Toxic  Effects  on  Humans:   Very  hazardous  in  case  of  skin  contact  (irritant),  of  ingestion.  Hazardous  in  case  of  skin  contact  (permeator),  of  inhalation.  Special  Remarks  on  Toxicity  to  Animals:   Not  available  Special  Remarks  on  Chronic  Effects  on  Humans:  Not  available  Special  Remarks  on  other  Toxic  Effects  on  Humans:  Not  available  12.     Ecological  Information  Ecotoxicity:   Not  available  BOD5  and  COD:   Not  available  Products  of  Biodegradation:   Possibly  hazardous  short-­-term  degradation  products  are  not  likely.  However,  long-­-term  degradation  products  may  arise.  Toxicity  of  the  Products  of  Biodegradation:  The  products  of  degradation  are  more  toxic.  Special  Remarks  on  the  Products  of  Biodegradation:  Not  available.  13.   Disposal  Considerations  Disposal  Methods:   Dispose  of  in  accordance  with  local  authority  requirements.  14.   Transport  information  DOT  Classification:   CLASS  6.1:  Poisonous  material  Identification:   Toxic  solid,  organic,  n.o.s.  (Capsaicin):  UN2811  PG:  III  Special  Provisions  for  Transport:   Not  available  15.     Regulatory  Information  Federal  and  State  Regulations:   TSCA  8(b)  inventory:  Capsaicin  Other  Regulations:       OSHA:     Hazardous  by  definition  of  Hazard  Communication  Standard  (29  CFR1910.1200).  Other  Classifications:       WHMIS  (Canada):     CLASS  D-­-1B:  Material  causing  immediate  and  serious  toxic  effects  (TOXIC).  CLASS  D-­-2B:  Material  causing  other  toxic  effects  (TOXIC).     DSCL  (EEC):     R38-­-  Irritating  to  skin  R41-­-  Risk  of  serious  damage  to  eyes     HMIS  (U.S.A.):     Health  Hazard:  3  Fire  Hazard:  1  Reactivity:  0  Personal  Protection:  E     National  Fire  Protection  Association  (U.S.A.):    Health:  3  Flammability:  1  Reactivity:  0  Specific  hazard:     Protective  Equipment:     Gloves,  lab  coat,  dust  respirator,  splash  goggles.  Be  sure  to  use  an  approved/certified  respirator  or  equivalent.  Wear  appropriate  respirator  when  ventilation  is  inadequate.  16.   Other  Information  DISCLAIMER:  Every  effort  has  been  made  to  ensure  that  this  information  is  accurate  and  up  to  date.  Users  are  reminded  that  they  should  ensure  that  they  have  retained  or  internally  circulated  the  most  up  to  date  copy  as  provided  to  the  persons  or  work  locations  that  require  them.  No  warranty  is  implied  or  given  as  to  suitability  for  use  for  any  activity  that  is  not  covered  by  either  the  technical  data  sheet  or  restrictions  of  use  as  above.