Analytical Systems Articles

  • How data and analytics are keeping Philly’s water safe

    CH2M assisted Philadelphia to implement a Surveillance and Response System (SRS) demonstration project under the U.S. Environmental Protection Agency’s (EPA’s) Water Security Initiative. CH2M Global Director Smart Cities and Senior Technology Fellow Dr. Avinash S. Patwardhan and Ken Thompson, CH2M Deputy Director Intelligent Water Solutions and Senior ...


    By CH2M Hill Companies, Ltd.

  • Webinar Highlights: Microfluidics for macromolecules

    Hi, I’m Jim Murphy, Principal Consulting Chemist at Waters, and I recently collaborated with Lucinda (Cohen) Hittle to present an exciting webinar on the use of microflow chromatography for macromolecules.  Lucinda, a Director of Discovery Bioanalytics at Merck, presented an overview of the use of LC-MS for peptide analysis along with various case studies for in vitro and in vivo ...


    By Waters Corporation

  • 5 Reasons to automate a Process Development Lab

    5 Reasons why you should automate a Process Development Lab Higher throughput Increased success rate Reduced resource requirement Improved technical transfer and scale-up readiness Significant Return on Investment We can show how a networked PD and/or MSAT lab bioreactor automation system can dramatically improve lab productivity, increase ...


    By Broadley-James Ltd

  • Using Devices and Analytics in Safety

    Technology touches virtually everything we do in modern society and in EH&S, it is becoming more prevalent by the day. Businesses can now use analytics and devices to vastly improve their safety strategy and, thanks to data that is obtainable from both humans and connected machines, make much smarter, strategic EH&S decisions. The rise of the ...


    By Rivo Software Ltd.

  • Comparison of simple ozonation and direct hydrogen peroxide processes in TNT removal from aqueous solution

    Oxidation of 2,4,6-trinitrotoluene (TNT) using simple ozonation and direct hydrogen peroxide was studied. An analytical method based on the HPLC (high performance liquid chromatography) system was used for TNT detection. The influence of parameters such as pH of the solution (3–10), initial TNT concentration (10–100 mg/L), dosage of ozone (0.2–1 g/hr), H2O2/TNT molar ratio (250–1,000), ...


    By IWA Publishing

  • Method Scaling in Preparative HPLC: Analytical Method & Preparative Method

    VOC:  “I tried to scale up my analytical HPLC method to prep and it didn’t work.” Andy:  This is one of the most common things we hear from chemists wanting to do preparative chromatography. We also hear the following question pretty often too: VOC:  “I have a good analytical HPLC method, how do I scale it to ...


    By Waters Corporation

  • What is microflow?

    What are the differences between micro-scale and conventional LC? Microflow (aka micro-scale) LC/MS has been widely applied to proteomic research for years.  Recently, as microflow LCMS systems continue to evolve, more and more laboratories in various fields are weighing the implications of applying this small-is-beautiful technology. In this and my next two blog posts, ...


    By Waters Corporation

  • Meeting the Need for LIMS at a smaller laboratory case study

    EMS Inc (Environmental Management Services) offers environmental sample collection, VELAP (Virginia Environmental Laboratory Accreditation Program) accredited laboratory analysis, water and wastewater plant operations, and consulting services to both industrial and commercial clients. By introducing Autoscribe's entry level Matrix Express LIMS (Laboratory Information Management System), EMS Inc ...


    By Autoscribe Informatics

  • Matrix Gemini LIMS at work a Contract Analysis Laboratory Case Study

    DM Scientific, a rapidly growing contract analysis laboratory for the Animal Feed Industry, has replaced its largely manual sample tracking and reporting system based on a spreadsheet with the Matrix Express 'out of the box' LIMS (Laboratory Information Management System) from Autoscribe. With previous experience of using Matrix Express ensuring an even faster than normal implementation the ...


    By Autoscribe Informatics

  • ACQUITY Arc System: Transferring Validated HPLC Methods within USP Guidelines

    The thought of transferring established high performance liquid chromatography (HPLC) methods onto a another vendor’s LC, or a new platform like UHPLC/UPLC, may cause a bit of anxiety for those that may be unaware of how easy it can be. The reason that the topic of analytical method transfer induces so much angst is that for the transfer of an LC method to succeed, the method has to work as ...


    By Waters Corporation

  • Effective Use of the ACQUITY QDa Mass Detector with Your LC: A Q and A with Dr. Tom Wheat

    I recently presented a webinar describing some techniques and tools used for effectively using the QDa Mass Detector with liquid chromatography systems. Several attendees submitted questions that may be of general interest to a broader audience. It is better, as you said, to use negative mode for ...


    By Waters Corporation

  • Predicted and observed therapeutic dose exceedances of ionizable pharmaceuticals in fish plasma from urban coastal systems

    Instream flows of the rapidly urbanizing watersheds and estuaries of the Gulf of Mexico in Texas (USA) are increasingly dominated by reclaimed waters. Though ionizable pharmaceuticals have received increasing attention in freshwaters, many research questions remain unanswered, particularly in tidally influenced urban coastal systems, which experience significant spatiotemporal variability in ...


    By John Wiley & Sons, Ltd.

  • Beyond Incident Rates: Use the Power of Leading Indicators to Improve EHS Performance

    What if you were driving somewhere, and could only see backwards in the rear-view mirror? Sounds scary, but this is pretty much how traditional Environmental, Health and Safety (EHS) metrics like incident and injury rates have been used for decades to manage performance. Such lagging indicators measure what occurred in the past. They give you a good view of where you’ve been, but not where ...


    By Rivo Software Ltd.

  • A tool for evaluation of lifecycle cost of water production for small-scale community projects

    The aim of this study is to develop an analytical tool to estimate lifecycle cost for water service provision for small-scale community water projects. The primary objective is to provide an analytical estimation tool to governments, funding agencies and communities to ensure sustainability of water projects. The secondary objective is to use the tool as an industry benchmarking aid to empower ...


    By IWA Publishing

  • Optimal closure of system actuators for transient control: an analytical approach

    The effect of downstream valve closure scheduling was analyzed to find optimal closure parameters that lead to the minimal maximum pressure head in the water distribution system. Several valve closure strategies were explored, combining the known valve performance curve (change in flow as a function of change in valve's opened area) with unknown valve closure curve (change in valve's opened ...


    By IWA Publishing

  • A global assessment of basin plans: definitions, lessons, recommendations

    Basin plans have become a core element of water management in the 21st century. Systematic analytical scrutiny of the contents of basin plans is nonetheless scant. This paper develops a framework for assessing basin plans and systematically applies it to understand how contents of basin plans vary. The paper synthesizes a definition of ‘basin plan’, generates a classification system for basin ...


    By IWA Publishing

  • Developing a joint operation framework for complex multiple reservoir systems

    This study aims to present a joint operation framework for complex multiple reservoir systems to balance water supply between subsystems and between different stakeholders, and support decisions about water releases from the entire system and individual reservoirs effectively. The framework includes three steps: (1) aggregated virtual reservoirs and various subsystems are established to ...


    By IWA Publishing

  • Delineation of potential sites for rainwater harvesting structures using a geographic information system-based decision support system

    This paper presents a methodology based on a decision support system (DSS) that employs remote sensing and field survey data and geographic information system (GIS) to identify potential rainwater harvesting areas (RWH). This DSS was implemented to obtain suitability maps and to evaluate the existing RWH structures in the study area. The DSS inputs comprised maps of rainfall surplus, slope, ...


    By IWA Publishing

  • Comparison of commercial analytical techniques for measuring chlorine dioxide in urban desalinated drinking water

    Most drinking water industries are closely examining options to maintain a certain level of disinfectant residual through the entire distribution system. Chlorine dioxide is one of the promising disinfectants that is usually used as a secondary disinfectant, whereas the selection of the proper monitoring analytical technique to ensure disinfection and regulatory compliance has been debated ...


    By IWA Publishing

  • Water resource accounting for Uganda: use and policy relevancy

    This paper uses the system of economic and environmental accounting for water to demonstrate how the water sector interacts with the social-economic sectors of the economy. Furthermore, it reviews the existing institutional and policy framework in Uganda, and proposes an analytical framework which can be used to provide sound inter-sectoral planning in order to achieve sustainable water ...


    By IWA Publishing

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