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BioSPXModel Ampha X30 -Single-Cell Analysis Instrument

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The Ampha X30 represents a significant advancement in the field of single-cell analysis, utilizing impedance flow cytometry to deliver outstanding results without the need for dyes or incubation. This versatile instrument is capable of handling a wide array of cell types, including bacteria, human and animal cells, algae, and yeast, leveraging different microfluidic chip sizes for comprehensive analysis. It efficiently measures cell count, viability, and metabolic activity in minimal time, offering direct measurement through its patented microfluidic chip with integrated microelectrodes. The absence of traditional dyes ensures cells remain intact for potential reuse in applications such as sorting or tissue culture, reducing both time and cost. Operational flexibility allows for online analysis within a reaction solution, and sophisticated software aids in data interpretation. Amphasys technology excels in measuring cells ranging from 1 to 50 micrometers and beyond, ensuring high sensitivity across all cell sizes.

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Discover how you obtain more cell information

Impedance Flow Cytometry provides a straightforward and cost-efficient solution for single-cell analysis, eliminating the need for dyes, markers, and incubation. Cell information like cell viability, cell count, and cell metabolic status can be determined quickly and with minimal effort.

  • Viability, counting, cell metabolic status, including apoptosis
  • Real-time monitoring of cell cultures
  • Label-free analysis of all cell types
  • Works with turbid, opaque, and auto-fluorescent media
  • Cost-efficient in investment, maintenance, and cost per sample
  • Portable and desktop solutions

Cell Analysis with Ampha X30

The novel Ampha X30 opens a new era of cell analysis: simultaneous measurement of cell count and cell viability, and in addition more information about the status of the cells, like metabolic activity. Results are available after minutes – including sample preparation! With one instrument and four different chip sizes of the microfluidic chip the whole range of cells can be measured: bacteria, human and animal cells, algae, yeast, and others like somatic cells in milk.

all cell types can be analyzed with one instrument, using chips with different channel diameters. The cells are not harmed by the measurement and due to the absence of dyes and markers, the cells can be recovered and reused, e.g., for sorting or tissue culture.

Efficient

For the sample preparation no markers or dyes are required which reduces the operational cost. In addition, no incubation time is needed which shortens the whole measurement to minutes – from sample preparation until the result.

Flexible

The instrument is highly flexible and can be used for online analysis via a bypass of the reaction solution. The sample can be pumped from the reactor directly through the microfluidic chip and back into the reactor. The sophisticated software thereby facilitates measurement and data analysis and integrated wizards promote a simple workflow.

 

Get information about any cell, any size

Amphasys technology measures a wide range of cell sizes — from 1 to 50 μm and beyond. From bacteria and yeast to mammalian cells and even spheroids, our electrical detection method allows accurate analysis of cell count, viability, and metabolic activity, regardless of size or media.

Label-Free Analysis

No dyes. No markers. No incubation. Amphasys enables direct measurement of cells without laborious sample preparation, delivering fast, accurate data. And because we don’t alter your cells, they remain intact for reuse in sorting or tissue culture.

Cell analysis with patented biochip technology

The heart of the cytometer consists of a patented microfluidic chip equipped with microelectrodes. This high-sensitivity sensor measures changes of the electrical resistance (impedance) of the fluidic medium when cells or other particles pass through the applied electric field.

To ensure the highest possible sensitivity, Amphasys provides chips of different diameters for the whole range of small to large pollen cells (up to 200 µm).