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- Sepax Unix - Model C SEC-300 - Columns
Sepax Unix - Model C SEC-300 -Columns
Utilizing proprietary innovative surface technologies, Unix™-C SEC-300 phase is made of uniform, hydrophilic, and neutral nanometer thick films chemically bonded to high purity and mechanically stabilized silica with the particle size of 1.8 µm. The combination of small particle size and large pore volume of Unix™-C SEC-300 renders the highest separation efficiency and resolution of analytes. The well-controlled surface chemistry results in excellent lot-to-lot reproducibility. The unique bonding chemistry, coupled with the maximized bonding density, allows Unix™-C SEC-300 to provide high stability and negligible non-specific interactions.
Unix™-C, uses lay-down monolayer on porous silica (as shown below), offers ideal phase chemistry for the separation of all biological sample types including challenging hydrophobic samples such as antibody drug conjugates (ADCs), hydrophobic mAb and its fragments, bispecific mAbs (BsMAbs), PEGylated proteins, glycoproteins, fusion proteins, membrane proteins and oligonucleotides.
- Phase: UnixTM-C SEC-300
- Material: Neutral, hydrophilic film bonded silica
- Average Particle size: 1.8 µm
- Pore size: 300 Å
- Protein MW range (native): 5,000 - 1,250,000 Da
- pH stability1: 2.0 - 8.5
- Mobile phase compatibility: Aqueous and organic
- Suggested salt concentration: < 0.5 M
- Recommended flow rate range for maximum column lifetime: 0.1 - 0.35 mL/min
- Recommended operating column backpressure for maximum column lifetime: < 4,500 psi
- Suggested operating temperature for optimal column lifetime: 10 - 30°C
- Particle size of 1.8 µm with a pore size of 300 Å
- Ultra-high separation efficiency, recovery, and resolution
- High stability and lot-to-lot reproducibility
- Innovative surface chemistry for minimized secondary interactions
- Reduced dependency on organic additives for hydrophobic samples
- Ideal for all sample types including challenging hydrophobic samples like ADCs, bsMAbs, PEGylated proteins, glycoproteins, fusion proteins, membrane proteins, and oligonucleotides.
- Great tool for universal platform high throughput method screening (HTS)
- Compatible with both UHPLC and HPLC