Massive Photonics - Model Massive-SDAB-FAST ANTI-PDL1 -Direct Target Labeling Kit for DNA-PAINT Imaging
The Direct Target Labeling Kit is designed for DNA-PAINT imaging, offering ready-to-use binders that facilitate the visualization of various proteins. This kit is particularly useful for imaging PD-L1, CTLA-4, CD45, Synaptotagmin-1, VGLUT1, PSD95, Bassoon, Tau, and Map2. It includes single-domain antibody (sdAB) binders that are specific to target proteins and are integrated with the FAST DNA-PAINT sequence for effective docking. Each sdAB is coupled to a dedicated DNA-PAINT docking strand. The kit encompasses imager strands and buffers necessary for sample preparation and imaging processes. Developed by NanoTag Biotechnologies, these sdABs are sold under license and are available as unmodified or fluorophore-coupled variants. For versatile imaging applications, the MASSIVE-Actin kit can be integrated for super-resolution imaging of filamentous actin. This comprehensive kit is an essential tool for researchers requiring precise molecular imaging in cellular environments.
This kit provides ready-to-use binders for DNA-PAINT imaging of PD-L1, also known as Programmed Cell Death Ligand 1. PD-L1 is a transmembrane protein that plays a critical role in immune regulation by binding to its receptor PD-1 on T cells. Also included are imager strands and buffers for sample preparation and imaging.
This kit contains single-domain antibody (sdAB) binders that recognize PD-L1 and are coupled to FAST DNA-PAINT sequence F1. Each sdAB is coupled to a single DNA-PAINT docking strand.
sdABs developed and manufactured by NanoTag Biotechnologies are sold under license. Unmodified and fluorophore- coupled sdABs (FluoTag®) remain available for direct purchase from NanoTag Biotechnologies.