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Ehrfeld FlowPlate - Model Lab, A6 & A5 -Microreactors for Efficient Process Intensification
FlowPlate microreactors offer a versatile solution specifically designed to tackle the challenges faced by the pharmaceutical and fine chemicals industries, such as the need for small, adaptable production quantities with high-quality demands and rapid market introduction. These reactors, which are developed by Lonza and distributed worldwide by Ehrfeld Mikrotechnik, allow for the development and production of active pharmaceutical ingredients (APIs) and fine chemicals. The modular design of the reactors permits easy scaling from laboratory to production scale with flow rates up to 20 L/h. The units can be operated up to 100 bar and 200°C, presenting new processing opportunities while maintaining safety through rigorous cGMP standards. Each reactor offers a unique, closed one-channel design that avoids dead volume and facilitates easy cleaning and maintenance, making them suitable for campaigns requiring rapid transitions between different processes.
Small, frequently changing product quantities, demands of high quality and a short time-to-market – these are the major challenges in the pharmaceutical and fine chemicals industries. Our innovative solution: the FlowPlate microreactors. With this premium device, developed by Lonza and exclusively distributed worldwide by Ehrfeld Mikrotechnik, active pharmaceutical ingredients (APIs) and fine chemicals can be developed and produced more competitively.
The simple and fast scale-up exactly meets your requirements to be competitive on a global scale: Campaign-by-campaign production on demand under cGMP conditions up to tonne scale and all this achieved within a very short time. Our FlowPlate devices can be operated up to 100 bar and open up new process windows for your processes. The compact design can be expanded modularly – reactor plates with different channel designs can be interchanged freely even in the already assembled reactor. The construction can be flexibly adapted to specific customer requirements and process tasks. Clean-in-place protocols can be implemented easily due to the FlowPlate’s one-channel-design which is free of dead volume and sealing materials.
Different mixing structures, adapted to the nature of the process (be it homogeneous, heterogeneous liquid-liquid, gas-liquid), offer a unique concept for individual process intensification.
The FlowPlate microreactors offer an innovative closed one-channel design – with clear advantages for the process:
- volume flows from laboratory scale of a few mL/min to production at 20 L/h and more
- simple and fast scale-up due to channel sizing-up under almost constant process conditions
- very high heat transfer capacity
- simple process control
- flexible adaptation to different reactions due to rapid exchange of process plates: homogeneous: SZ or TG structure, liquid-liquid / gas-liquid: LL structure
- safe handling of hazardous reagents
- can be used up to a pressure of 100 bar and temperatures up to 200 °C
- no passive volume meaning that residues in the channel can be avoided (CIP = cleaning-in-place)
- easy cleaning and maintenance, ready for cGMP