MDX - Multiferm Cell Culture Nioreactor

"MultiFerm"   is an automated and easy-to-use 12-fold fixed-bed fermenter system of the   parallel cultivation of sensitive animal, human and other shear sensitive   cells which are without stable cell wall. The system is used in the   production of monoclonal antibodies, cultivation of adherent and recombinant   cells and in the cell-physiological studies of tissue cells as example tumour   cells, primary cells, stem cells, liver and kidney cells. The fixed-bed system   is equipped with the necessary measurement and control facilities, probes and   sensors, peristaltic pumps, gas supply, control program and computer for   saving, evaluation and transfer of the data to other computers. The system   consists of an outer 1.5 l media conditioning vessel and 12 inner fixed bed   reactors which are made of Duran glass and are fitted in the middle of the   media conditioning vessel. The conditioning vessel is made of Duran glass   also. This makes it possible to watch, to check and to control the   development of the cell cultivation. The lid, the in and out leads are made   of insensitive PEEK material to protect the sensitive cells from damages by   free metal ions by the usual metal lids. The fixed-bed material consists of   highly porous glass sinter pearls or other suitable carrier materials and is   inside the fixed-bed reactors. The cells are transferred to the surface of   the carrier material in the fixed-bed reactors and grow and increase on,   around and between the carrier materials and can be used for further tests   and examinations.

Depending   on cell-types and growth conditions "MultiFerm" is best suited for   the parallel cultivation of the same or different cell lines which grow under   the same or almost the same growth-conditions.

The fermenter   system is excellently suited for pre-testing and testing of medicine,   biotechnology, pharmaceutical and food industry.

• Total volume 1.5 Litre
• Working volume 12 x 10 ml   fixed-bed reactors
• Working principle Axial
• Sterilization Autoclaving
• Temperature ranges 5 – 60o   C
• pH ranges 3 - 10
• Pumps for circulation   of media and continuous cell cultivation
• Flow rates 12 x 0.15 – 3   ml/min
• Heating directly via   heating stick
• Operation Batch, Fed-Batch,   continuous
• pH regulation Acid, alkali or   CO2
• Gas-additions (outer vessel) Air, O2,   N2, CO2
• Gas humidification yes
• Waste gas condenser yes
• Sampling system yes
• Diving pipes yes
• Electrodes and cables yes
• Light on request
• Process control system yes
• PC interface yes
• Data acquisition yes
• Data saving yes
• Data transfer to other computers Yes