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Model BeatBox -Tissue Homogenization & Cell Lysis

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The challenge: Reproducible and reliable cell lysis and tissue homogenization needs to produce a smooth and easy to pipette homogenate and minimize the possibility of cross-contamination. A specific consideration for proteomics is the release of the maximum number of proteins to make them accessible for the next steps of sample preparation. Additionally, lab space, the requirement for chiller units, and the noise made by some processes can also impact instrument choice.  The solution: The BeatBox® is a fast and easy to use instrument for up to 96 samples, which completes the homogenization in as little as 10 minutes without sample cross contamination and minimal heat induction. The BeatBox® has a surprisingly small footprint and quiet operation in comparison to traditional tissue processing machines. With the BeatBox®, cell lysis and tissue homogenization can be integrated into the PreOmics® iST sample preparation workflows.

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1. Preparing samples

Cut tissue into appropriate size or volume of cells

2. BeatBox Tissue Add-on Kit

Add your tissue or cells and the LYSE buffer from iST kit family

3. BeatBox your samples

Select the power and time, then press START

4. Digest and clean-up

Continue with step 2 from selected iST workflow

5. MS analysis

Inject and analyze your samples

BeatBox homogenates show the highest protein yields. Reproducibility of protein yields from different tissues were increased by 2.5x using BeatBox

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Cell lysis and tissue homogenization simplified
  • Add tissue or cells and lysis buffer; then select your settings in just two clicks for a perfectly homogenized sample
  • Maximum protein release in 10 minutes
  • 1-50 mg of wet tissue or up to 1e7 cells
  • Minimize heat induction and the possibility of cross contamination
Relax
Flexibility and efficiency combined
  • Versatile, it can homogenize multiple tissue and cell types
  • Optimized programs depending on tissue type
  • Flexible throughput; 96 well or 24 single tube format
  • Superior reproducibility
Realize
Next generation technology - today!
  • Small footprint
    >> L 40 x H 26 x W 24 cm - 5kg
    >> L 16" x H 10" x W 10" - 12lbs
  • 7" touch screen simplicity
  • Utilizes PreOmics® Tissue Homogenization kits and GYUTO bead technology
  • Seamlessly compatible with iST workflows for even greater efficiency