A spinoff of Case Western Reserve University, the company was founded by Prof. Paul V. Lehmann and scientists working with him on immune monitoring with the intent to help fellow scientists in their respective immune monitoring efforts. CTL maintains an active immune-monitoring-focused research program presently employing 22 M.D./Ph.D.- level scientists to extend the limits of immune monitoring, and to share the expertise gained with the research community.

CTL Headquarters, Building A, in Shaker Hts, OH

CTL is the only company that, for over 25 years, has focused on advancing ALL ASPECTS of immune monitoring by ELISPOT/FluoroSpot (collectively called ImmunoSpot^®):

Developing and manufacturing hardware and software solutions for scientifically validated ImmunoSpot^®data analysis that are suited to serve the advanced needs of both the academic as well as the regulated research community.
Developing and manufacturing ImmunoSpot^®test kits that not only have ultimate sensitivity for each analyte, but also permit unambiguous detection of analyte co-expression patterns in multicolor assays.
Developing and manufacturing all other reagents that are critical for the optimal performance of the assay, including serum-free test media that have been formulated for low background and high signal performance in ImmunoSpot^®assays, or for functionally loss-free freezing and thawing of PBMC.
Developing and offering positive control antigens for T cell ImmunoSpot^®testing.
Building and offering an extensive library of PBMC that provides scientists ready access to human subjects’/cohorts’ fully functional PBMC that bear genetic or environmentally imprinted traits of their interest. These cells are also ideal for studies of cellular immune functions while accounting for the diversity within the human population. Fully-functional, these cells are ideal as reference standards and for assay development, qualification, and validation.

Our Contract Research Organization (CRO) implements cellular immune monitoring for our clients.

CTL’s Mantra

To help science progress by:

pioneering immune monitoring and elevating it to an exact science
creating hardware and software solutions that enable objective, transparent, and documented morphometric analysis
creating reagent solutions that standardize and expedite immune monitoring
supporting clinical trials and scientific efforts in immune monitoring
narrowing the gap between basic immunology and its application in health care

Doing meaningful work at CTL

Being able to contribute to something larger than life is essential for living a fulfilled life. At CTL, we take pride in helping science progress in the field of immune monitoring. Our ImmunoSpot^®technology enables scientists to learn more about how the immune system works in health and disease, thus facilitating the diagnosis and treatment of infectious diseases, cancer, allergies, transplantation, and autoimmune conditions. Directly, or indirectly, all CTL employees serve this mission, either by being engaged themselves in cutting edge research, or by enabling our customers in such research. Whether doing laboratory experiments, writing software, building readers or kits, or performing contract research, whether growing and characterizing our ePBMC library, or working in CTL’s Customer Support Team, we all work as a team toward the same goal: to pioneer immune monitoring.

Model Human GM-CSF -Single-Color ELISPOT

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