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Nicoya OpenSPR - Benchtop Surface Plasmon Resonance Instrument
OpenSPR is a benchtop Surface Plasmon Resonance (SPR) instrument designed to provide high-quality, label-free interaction analysis at an affordable cost. It is particularly known for its nano-structured sensor surface that leverages localized SPR (LSPR) to deliver highly sensitive and reproducible kinetic data. This system is tailored for a broad spectrum of applications in both biotechnology and academia, suitable for tasks such as lead optimization, drug discovery, quality control, and validation. Its user-friendly interface ensures swift setup and operation, facilitating integration within various experimental workflows. The instrument is widely adopted by researchers and offers an accessible alternative to more expensive, shared facilities for SPR analysis, promoting innovation in scientific research.
OpenSPR is the world’s only benchtop surface plasmon resonance (SPR) instrument. It provides high quality, label-free interaction analysis for a fraction of the cost of existing solutions. Our unique nano-structured sensor surface uses localized SPR (LSPR) to deliver repeatable, highly sensitive kinetic data.
Compatible Molecules:
- Proteins
- Peptides
- Antibodies
- Antibody variants
- Nucleic acids
- Lipids
- Adeno-associated viruses (AAV)
- Virus-like particles (VLPs)
- Hormones/cytokines
- Small molecules (application dependent)
Supported Assays:
- Kinetics/affinity characterization
- Concentration analysis
- Yes/No binding
- Competition assays
- Epitope mapping
Performance
- Association Rate (kon) : 1×103–1×107 1/M*s
- Dissociation Rate (koff) : 0.1–1×10⁻⁵ 1/s
- Affinity Range (KD) : mM-pM
Hardware
- Number of Channels : 2
- Flow Rate : 5–200 μL/min
- Injection : Semi-Automated
- Injection Volume : “50, 100, 250 or 500 μL (100 μL standard)”
- Sample Volume : 200 μL
- Sample Capacity : Injection volume + 50 μL
- Autosampler : Optional upgrade to OpenSPR-XT
- Temperature Range : 4°C – 40°C (lower limit 10°C below ambient temperature)
- Temperature Precision : +/- 0.25°C
- Buffer Switching : “3 ports available, automated switching”
- Instrument Sizehv : 46 x 34 x 21 cm
- Weight : 17 kg
- File Output : “CSV, TXT compatible with TraceDrawer.”
Get started on your experiments in a matter of hours.
OpenSPR is user-friendly and has versatile applicability. In smaller companies, the OpenSPR allows researchers to finish off their full experimental workflows at a low cost. In larger companies, the OpenSPR is easily integrated alongside their other assays.
OpenSPR is ideal for:
- Lead Optimization
- Quality control
- Drug discovery
- Validation
- Feasibility
Our mission is to improve human life by helping scientists succeed.
By using innovative nanotechnology, we reduce the cost and complexity of SPR instrumentation and make it accessible to every researcher. Having OpenSPR in your own lab will eliminate the expensive costs and inconvenient travelling associated with using a shared instrument in a core facility.
OpenSPR is helping over 600 researchers publish in high-impact journals worldwide.