Nicoya Lifesciences Inc. products

The Alto Digital Benchtop SPR System, introduced by Nicoya Lifesciences, marks a significant advancement in the field of surface plasmon resonance (SPR) technology. It is the first SPR instrument to combine digital microfluidics with nanotechnology-based biosensors, revolutionizing fluidics interactions through disposable, integrated microwell plates. Alto's design enables precise management of 2µL sample volumes while accommodating crude samples without requiring fluidics maintenance. Highly compatible with automated processes for both hardware and software, Alto provides efficient sample-in/answer-out data with leading throughput and offers over 24 hours of autonomous operation. Its user-centric design incorporates a flexible 16-channel setup and an intuitive data analysis platform to enhance ease of use. The system supports applications such as kinetics and affinity characterization, quantitation, and epitope mapping, and works with a wide range of sample types, including proteins, nucleic acids, viruses, and small molecules. Additionally, the integrated Nicosystem software streamlines data acquisition and analysis, promoting accessibility and remote collaboration.

OpenSPR is a benchtop Surface Plasmon Resonance (SPR) instrument designed to provide high-quality, label-free interaction analysis at an affordable cost. It is particularly known for its nano-structured sensor surface that leverages localized SPR (LSPR) to deliver highly sensitive and reproducible kinetic data. This system is tailored for a broad spectrum of applications in both biotechnology and academia, suitable for tasks such as lead optimization, drug discovery, quality control, and validation. Its user-friendly interface ensures swift setup and operation, facilitating integration within various experimental workflows. The instrument is widely adopted by researchers and offers an accessible alternative to more expensive, shared facilities for SPR analysis, promoting innovation in scientific research.

OpenSPR Sensors, developed by Nicoya Lifesciences, are designed to provide a cost-effective solution for surface plasmon resonance (SPR) applications. These sensors harness advanced nanotechnology for manufacturing, which results in a significant decrease in expense compared to traditional SPR sensors, while maintaining exceptional quality standards that ensure reliable and repeatable measurements. With a coefficient of variation (CV) of less than 5% across critical optical properties, these sensors offer stability in diverse environments, accommodating a range of solvents, buffers, and reagents. Notably compatible with both OpenSPR and OpenSPR-XT instruments, OpenSPR Sensors enable researchers to conduct numerous experiments economically. The High Sensitivity Sensors variant enhances localized sensitivity, proving advantageous for small molecule analysis and improving signals of larger biomolecules, thus extending the applications of SPR technology.