YMC Europe GmbH

YMCModel pH-stable -Stationary Phases

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To overcome the limitations of traditional silica-based stationary phases regarding the chemical stability, hybrid silica-based phases have been developed. Hybrid silica contains organic groups within the silicon dioxide network, making it more resistant to a wider pH range. The innovative preparative stationary phase YMC-Triart Prep combines mechanical strength and pH stability. It is stable up to pH 10 which allows more flexibility for process development. Moreover, efficient cleaning-in-place (CIP) procedures can be applied! From real-life process development examples, YMC-Triart Prep has been shown to outperform traditional silica-based materials in terms of stability up to 4-fold. Longer column lifetimes lead to greater amounts of product being produced per kilogram of stationary phase. The results mean improved production procedures and reduced overall costs.

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