Nanolytics GmbH
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Advanced Biomolecular Interaction Analysis System

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Nanolytics GmbH specializes in the detection and characterization of biomolecular interactions, specifically focusing on protein-protein and protein-ligand interactions. Their innovative use of Analytical Ultracentrifugation (AUC) provides detailed insights into complex stoichiometries, dissociation constants, and reaction kinetics, crucial for biochemical and pharmacological research. The company's expertise extends to utilizing advanced multiplex analysis resources such as 4D AUC and AIDA, enabling in-depth analysis of multi-component systems. A case study highlighted their ability to analyze antibody-antigen interactions in a two-component mixture, showcasing the power of their multi-signal analysis. This allows for accurate determination of stoichiometry and apparent molar mass in complex mixtures, offering a robust toolset for researchers in drug development and therapeutic research. Their extensive experience and specialized algorithms ensure optimal analysis conditions and comprehensive interaction characterization.

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The detection and characterization of biomolecular interactions, in particular protein-protein and protein-ligand interactions as well as their formation dynamics and kinetics, are essential tasks in biochemical and pharmacological research.

AUC provides superb capabilities for analyzing and obtaining complex stoichiometries, dissociation constants, and reaction kinetics of relevant systems, such as antibody-antigen, drug-receptor, and therapeutic protein-receptor binding.

Nanolytics offers the most advanced multiplex (multi-signal) analysis resources in AUC, i.e. 4D AUC and AIDA along with the expertise in applying specific data algorithms. This ensures optimal conditions for tackling multi-component systems and characterizing their biomolecular interactions.