Pace Analytical
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Solubility & Bioavailability Enhancement

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Pace® offers small scale feasibility and current Good Manufacturing Practices (cGMP) pilot scale processes for bioavailability enhancement of orally administered small molecules. Leverage our commercially proven approaches to boosting bioavailability for poorly water-soluble drugs through production of amorphous solid dispersions and nanoparticle dispersions. Our team can rapidly assess the feasibility of multiple bioavailability enhancement techniques when traditional approaches are not sufficient.

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  • Drastically increases dissolution rate and apparent drug solubility.
  • Capable of providing multi-fold increases in drug bioavailability.
  • Feasibility can be performed at gram scale making it suitable for early development.
  • Proven commercial track record.

  • Lab and pilot scale capabilities for R&D and GMP processing.
  • Capabilities to process solid dispersion intermediates into finished product.
  • Biorelevant dissolution studies of solid dispersions.
  • Solid state characterization of solid dispersions.
  • Physical stability studies.