Based on a network infrastructure a Chromatography Data System (CDS) integrates all instruments and client workstations together with a central data repository. This allows for multiple users to access and concurrently work with the central data repository and any connected instrument transparently from any connected client workstation. Within the client/server environment of a CDS you can configure as many clients and instruments as necessary, considering any licensing and resource limitations. All raw data (acquired signals), meta-data, and calculated results are stored centrally along with the computer-generated audit trail information.