WinGPC UniChrom - Gel Permeation Chromatography (GPC) / Size Exclusion Chromatography (SEC) Software

WinGPC UniChrom has been developed by experts for efficient, precise and fast analysis of macromolecules, biopolymers, proteins and complex polymer products providing unique features and tools.   

Connectivity and general information :

• Supported detectors and instruments
• local and network installation
• Client/Server solutions

Features :

• General features
• Supported methods
• Reporting options

Software Modules:

• Light scattering modules
• Viscometry module
• Copolymer analysis modules

Compliance :

• Concepts and tools for regulated labs
• Compliance with 21CFR part 11

Specifications

• PC and OS requirements
• Latest version and update information
• Version history

WinGPC Support

• WinGPC Newsletter
• Support tools

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WinGPC UniChrom`s modular design fits changing needs by offering a complete path of expansion: from single instrument up to Client/Server solutions, from one detector and conventional calibration up to multi-detection systems with advanced analysis methods. One system to learn, maintain and validate.

WinGPC UniChrom general features
Unique and Powerful Tools:

• 35% time and eluent saving with the overlaid injection feature
• fully automated sample database with preview and comprehensive search function for fast access to all sample information (method, raw data, meta data, results)
• ease of use through the clear user interface and the software wizards for advanced functions
• powerful overlays for chromatograms, results, calibrations with mathematical overlay calculation functions
• automatic, quick and interactive data evaluation and calibration even during sequence runtime
• optional internal standard correction / flow correction
• add modules to expand the analytical power of your system - any time, anywhere

WinGPC Results:

• average molar masses (e.g. Mn, Mw, Mz, PDI, peak area) for one or more peaks within a sample
• true molecular weight distributions w(log(M)) vs. log M
• cumulative distribution and number distribution
• molecular weight maxima, minima and inflection points
• amount above/below user selectable molecular weight limits (e.g. < 500 g/mol)
• compound identification, amount of compound (e.g for polymer, residual monomer, solvent, additives)
• sieve curves, user defined retention values (e.g. molar mass for 95% retention), pore sizes
• calculated intrinsic viscosity
• mass recover

with modules and multiple detection:

• intrinsic and specific viscosity, branching index g`, g` averages
• Mark-Houwink coefficients and structure information
• radius of gyration averages, branching information g, g averages, on-line dn/dc
• average chemical composition, comonomer distribution, copolymer average molecular weight
• skew and width of compositional distribution
• functionality distribution
• 2D plots with molecular weights and concentration

Supported methods
WinGPC UniChrom unifies all methods for GPC/SEC:
conventional GPC/SEC with

• narrow standard calibration
• broad standard calibration
• universal calibration using Mark-Houwink coefficients
• integral calibration
• detector calibration for concentration determination

GPC/SEC with light scattering detection for

• low angle light scattering detectors (LALLS)
• right angle light scattering detectors (RALLS)
• multi angle light scattering detectors (MALLS)
• incudes branching and structure investigation and determination of radius of gyration

GPC/SEC with viscometry detection for

• universal calibration with viscometer detection
• triple detection with RALLS detector
• triple plus detection with MALLS detector
• branching and structure investigation, measuring Mark-Houwink coefficients and intrinsic viscosity

GPC/SEC with mass spectrometry for

• ESI-MS
• MALDI
• Single Quad/Triple Quad

Advanced copolymer analysis

• investigation of chemical heterogeneity with composition calibration
• copolymer composition and molecular weight determination using dual detection
• Polymer-HPLC, LAC, LAC under critical condition
• end group analysis
• 2D chromatography combing two different separation techniques (HPLC, GPC/SEC, TREF, IC, CE, GC)

GPC/SEC methods for

• membrane characterization with sieve curve determination
• heparin analysis according to EP/DAB
• multi area evalation for multimodal samples