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Creative Biogene Monitoring Testing Services
29 services found
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
CRISPR/Cas9 Platform offers gene knockout mouse generation services for our clients. With experienced scientists and excellent gene editing platform, our staff has successfully generated various gene KO mice by using CRISPR/Cas9. We provide a one-stop KO mouse generation service that covers from sgRNA design and construct, pronuclear microinjection to Founders genotyping and breeding. We are ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Gene mutation is an important inducer for many diseases. With CRISPR/Cas9 system, it becomes possible to correct the mutated site in living cells. This technique is based on two factors, guide RNA and Cas9 nuclease. Guide RNA alters its sequence for different target sites, while Cas9 functions as a nuclease cutting double strand DNA. At the presence of template, homology directed repair pathway ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene is one of the leading biotechnology companies which has the expertise in providing residual DNA testing services and related products for customers worldwide. Creative Biogene's sophisticated equipments, advanced technologies and highly experienced staffs are available to perform residual DNA testing on a wide range of samples including monoclonal antibodies, recombinant protein ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free. ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Mitochondria is a complex cellular organelle involved in key metabolic pathways such as fatty acid oxidation, amino acid metabolism, Krebs cycle, and oxidative phosphorylation (OXPHOS). Creative Biogene provides a comprehensive range of Biofluid Biochemistry testing services to assist researchers in mitochondria-related disease ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
L-carnitine is a ubiquitous trimethylated amino acid that is instrumental in the transport of long-chain fatty acids (LCFA) across the mitochondrial inner membrane. Creative Biogene provides a comprehensive range of Biofluid Biochemistry testing services to assist researchers in mitochondria-related disease ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Creative Biogene uses Seahorse XF real-time ATP rate measurement platform to efficiently and accurately detect mitochondrial aerobic respiration oxygen consumption rate (OCR) and glycolysis extracellular acidification rate (ECAR), and then convert into mitochondrial respiration ATP, glycolysis ATP, and total ATP production ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Creative Biogene uses Seahorse XF real-time ATP rate measurement platform to efficiently and accurately detect mitochondrial aerobic respiration oxygen consumption rate (OCR) and glycolysis extracellular acidification rate (ECAR), and then convert into mitochondrial respiration ATP, glycolysis ATP, and total ATP production ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
The green fluorescent protein (GFP) is a protein composed of 238 amino acid residues (26.9kDa) that exhibits bright green fluorescence when exposed to light in the blue to ultraviolet range. Although many other marine organisms have similar green fluorescent proteins, GFP traditionally refers to the protein first isolated from the jellyfish Aequorea victoria. The GFP from A. victoria has a major ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Cat.No. CLKO-0001 Description The cell lysate is obtained from the homozygous knockout cell line developed by CRISPR/Cas9. Applications Validate the specificity of antibodies.As a negative control for functional assay. Introduction Gene knockout cell lysates are the cell homogenate in RIPA buffer made with double-knockout cell lines. The Gene knockout cell lines are developed by CRISPR. The ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene offers a comprehensive animal model efficacy assessment service, aiding in understanding the pharmacokinetics, pharmacodynamics, and therapeutic potentials of new drugs. We utilize a variety of animal models including genetically modified mice, zebrafish, and other species to accurately simulate human disease conditions. Our research focuses on evaluating drug efficacy in vivo, ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Cat.No. PMSAR-0014 Description The Cre-T2A-GFP saRNA will express a Cre recombinase with a nuclear localization sequence (NLS) and a green fluorescent protein (GFP). Applications Immunotherapeutics, antigen saRNA Formats aRNA solution Quality Control • Purity analysis: A260/230 • Integrity analysis • Endotoxin ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Bacterial endotoxins, found in the outer membrane of gram-negative bacteria are members of a class of phospholipids called lipopolysaccharides (LPS). LPS are not exogenous products of gram negative bacteria, implicated in the development of Gram-negative shock. The release of LPS from bacteria takes place after death and lysis of the cell. They can cause adverse reactions in sufficient ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Luciferase Reporter Cell Line - NALM6 is engineered to stably overexpress luciferase reporter gene. It is an ideal positive control for use in bioluminescence assays. In addition, NALM6 cells form tumors post implantation into immunocompromised mice. The in vivo growth of these tumors can be monitored using bioluminescent imaging. ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene provides a comprehensive cell bank characterization service for customers to ensure the biosafety and control of biological and biotechnological products. Based on leading-edge facilities and excellent platform, our experienced staff offer a wide range of assays to character cell bank according to ICH guideline Q5D. At Creative Biogene, we perform cell bank characterization ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene is an expert in plant genetic engineering and molecular biology. We have devoted many years of efforts in optimizing plant expression vectors to adapt to different plant species. We provide universal and customized plant expression vector construction services, covering from sequence optimization, gene synthesis/cloning, DNA fragment assembling, sequencing to plasmid preparation. ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Luc Reporter Cell Line-B16F10 is engineered to stably overexpress luciferase reporter gene. It is an ideal positive control for use in bioluminescence assays. In addition, B16F10 cells can form metastases in mouse lungs. The in vivo growth of metastases can be monitored using bioluminescent imaging. ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
CRISPR/Cas9 technology is rapidly evolving in an unprecedented way in the field of gene editing, with its core components: gRNA and Cas9 endonuclease. Cas9 targets the specific sequence in the genome under gRNA guidance and cleaves the DNA duplex at the target site to form a DSB nick. This, in turn, triggers DNA repair mechanisms: non-homologous end-linking (NHEJ) or homologous directed repair ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
RNA plays an important and diverse role in cells. It is part of ribosomes and spliceosomes and also shows catalytic activity. What many of these functions have in common is the interaction between RNA and protein. For example, specific tRNA binds with aminoacyl -tRNA synthetase during protein synthesis to translate genetic code, and ribonucleoprotein granule binds to RNA in post transcriptional ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Homology repair (HDR) is a natural DNA repair mechanism induced by DNA double-strand breaks (DSB). The CRISPR/Cas9 system generates DSB on the chromosome, resulting in DNA repair. In the presence of donor DNA, homologous directed repair (HDR) occurs and replaces the genetic information (insertion, removal or substitution) in the chromosome with new information from the donor DNA. crispr cas9 ...