DNA and RNA Diagnostics Articles

  • Virus detection: Fast, sensitive, and cost-effective with electrochemical testing

    This white paper discusses the possibilities of rapid, point-of-care virus testing using inexpensive and easy-to-use screen-printed electrodes that are produced with ISO 13485 certification ("Manufacturing of sensors for medical devices"). Compared with other methods, such as virus isolation cultures, enzyme-linked immunosorbent assay (ELISA), and other molecular methods, including polymerase ...


    By Metrohm AG

  • Clarification for vaccines

    Clarification for vaccines – the economic and efficient removal of cell debris and negatively charged molecules with FILTRODISC BIO SD and FILTRODISC R2U depth filter modules. The purification of vaccines is a critical step during their complex production process. Cells and cell debris, as well as unwanted contaminants such as host cell proteins (HCPs) and nucleic ...


    By Filtrox AG

  • Technology is the Spark, People the Glue

    Service is part of an $18 billion massive global industry where technology is the spark and people are the glue.  We are the customer experience economy with data the next currency, but it is what people spend on services that drive our economies.  And it is ...


    By IFS

  • Syringe Pump Applications In Bioscience & Biochemistry

    In an era when biochemical research goes down to a single cell or even a single molecule level, there is a constant demand for ever more precise equipment. Considering that an accurate administration of small amounts of liquid is an imperative in any contemporary biochemical laboratory, the past few decades saw a vivid evolution of syringe pumps, carefully constructed and adapted for targeted ...


    By Chemyx Inc

  • Manufacturer of custom nucleic acids, USA - Case Study

    "Precise vacuum control allows for effective evaporation of valuable heat-sensitive oligos at low temperatures." Company / Institution Manufacturer of custom nucleic acids, USA Product lines Laboratory ...


    By BÜCHI Labortechnik AG

  • Ozone effects on specific bacteria, viruses and molds

    Bacterial are microscopically small, single-cell creatures having a primitive structure. The bacteria body is sealed by a relatively solid-cell membrane. Ozone interferes with the metabolism of bacterium- cells, most likely through inhibiting and blocking the operation of the enzymatic control system. A sufficient amount of ozone breaks through the cell membrane, and this leads to the destruction ...

  • Foodstuff production - a culture of contradictions?

    Sample preparation of food stuffs with knife mills Again and again consumers are confronted with scandals in the foodstuff industry. The latest case is the Fipronil egg scandal in the laying hen farming in the Netherlands and in Lower Saxony (Germany). What actually do foodstuff producers and marketers do to avoid such cases? A lot, if you believe the rising costs in the area of modern ...


    By Fritsch Milling and Sizing

  • Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming

    A population of NK cells expressing the activating receptor NKG2C and the maturation marker CD57 expands in response to human CMV (HCMV) infection. CD3–CD56dimCD57+NKG2C+ NK cells are similar to CD8+ memory T cells with rapid and robust effector function upon restimulation, persistence, and epigenetic remodeling of the IFNG locus. Chronic antigen ...


    By Johnson Controls, Inc.

  • Best practices in microorganisms sample preparation with Precellys homogenizers | Download the White Paper

    Microorganisms, like bacteria, fungi, archaea, algae, protozoa, and viruses, known as microbes, play a critical role in many different phenomena. They are involved in climate change, nutrient cycling, biodegradation and diseases. In biotechnology, microbes can be used in a wide range of fields, such as the pharmaceutical industry to produce drugs, the environmental sector to help manage pollution ...


    By Bertin Instruments

  • Electrolysis Brine Chemical Concept

    Sodium hypochlorite mainly works by generating hypochlorous acid though hydrolysis, and the hypochlorous acid will decompose nascent oxygen further, whose strong oxidation will denature the protein of the virus and other substance, it leads to kill pathogenic microorganism. What’s more, hypochlorous acid can not only act on cell wall, virus’s outer shell, but also on the body of the ...

  • The Role Of Hydrogen Water Machine Japan

    In 2008, the hydrogen water generator was granted a Japanese patent. It is essentially different from the tourmaline cup and negative ion alkaline water that you have seen recently. The hydrogen-rich water has more than all known antioxidants such as vitamins A, C, E, and green tea. The negative potential reaches a surprising -500mV. Elimination of human malignant reactive oxygen species (free ...

  • MK-4101

    MK-4101 is a potent SMO Inhibitor of the Hedgehog Pathway, highly active against Medulloblastoma and Basal Cell Carcinoma. target:SMO In vivo: MK-4101 was highly efficacious against primary medulloblastoma and BCC developing in the cerebellum and skin of Ptch1+/- mice. In vitro: MK-4101 induce deregulation of cell cycle and block of DNA replication in ...


    By MedChemExpress LLC

  • Biotoxis qPCR detection kit is now available!

    Bertin Instruments has just released Biotoxis, its new all-in-one qPCR (quantitative Polymerase Chain Reaction) kit which enables multiple simultaneous pathogen detection: B. anthracis, Y. pestis and F. tularensis. These highly dangerous pathogens are considered to be the first potential biological weapons leading to lethal infection. In a context of global bioterrorism, the Biotoxis kit is ...


    By Bertin Instruments

  • Precellys, trusted reference used by researchers worldwide

    Over the last years, biology techniques have considerably evolved, whether it be with mass spectrometry protein analysis or multiplex protein analysis and nucleic acids with qPCR, or sequencing… All those techniques have reached sensitivity levels never reached before. In parallel to increased sensitivity, cost per point has become lower for all laboratories, broadening the possibilities ...


    By Bertin Instruments

  • Amino Acid Fermentaion Broth Clarification

    Amino acids are the basic unit of protein composition, most amino acids are produced by fermentation method. Fermentation broth is an extremely complex system and contains microbial cells, metabolites, unconsumed medium, etc. The traditional method such as centrifuge and plate and frame pressure filtration,  filtrate quality is poor, soluble protein, sugar, peptide, pigment and other ...


    By Jiangsu Jiuwu Hi-tech Co

  • Precellys tissue homogenizer selected as one of the eight latest advances in next-generation sequencing technology

    SelectScience showcases the latest technology and guidance for preparing samples for next-generation sequencing, quality control and whole genome sequencing methodology. A vast amount of information can be uncovered using RNA sequencing to analyze gene expression profiles. To achieve this, high-quality RNA must be obtained, making RNA extraction and purification a mandatory ...


    By Bertin Instruments

  • Best practices in mouse tissue sample preparation for RNA extraction with Precellys® evolution

    The lab mouse is the most commonly used mammalian model system for genetic research. Scientists from a wide range of biomedical field shave used the mouse because of its close genetic and physiological similarities to humans, as well as the ease with which its genome can be manipulated and analyzed.Sample preparation is a critical step before proceeding to molecular down-stream analysis. ...


    By Bertin Instruments

  • Protein Directed Evolution

    Protein directed evolution Library In vitro directed evolution of proteins is an artificially simulated natural evolution mechanism. It creates mutant protein that does not exist in nature or one that some of its enzyme properties are significantly enhanced by using modern molecular biology methods to create a large number of gene variants library and adopting sensitive directed ...


    By Synbio Technologies LLC

  • The History of CRISPR-Cas9

    The CRISPR (Clustered regularly interspaced short palindromic repeats) system was first identified in archaea as an adaptive defensive mechanism that confers resistance to foreign genetic elements. Later on, the CRISPR-Cas system was engineered into a versatile gene-editing tool enabling manipulation of protospacer adjacent motif (PAM) downstream DNA. Now, CRISPR-Cas9 has facilitated ...


    By Synbio Technologies LLC

  • What Are the Advantages of CRISPR-Cas9?

    The CRISPR-Cas9 system is perhaps the most remarkable recent breakthrough in genome editing technology. CRISPR is a ubiquitous family of clustered repetitive DNA elements present in 90% of Archaea and 40% of sequenced Bacteria. CRISPR arrays consist of interspersed identical REPEAT sequences (21-48bp) and ...


    By Synbio Technologies LLC

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